Alternativas de reemplazo esofágico: revisión de tema
DOI:
https://doi.org/10.30944/20117582.2701Palabras clave:
enfermedades del esófago, esofagectomía, esofagoplastia, anastomosis quirúrgica, estómago, colonResumen
Introducción. Posterior a una esofagectomía parcial o total, el reemplazo del esófago representa un reto para los cirujanos. La selección del sustituto dependerá de diferentes factores, tanto del paciente como del cirujano. Las alternativas disponibles son el estómago, segmentos del colon, el yeyuno supercargado o colgajos libres miocutáneos.
Métodos. Se realizó una búsqueda de la literatura en las bases de datos de Medline, Embase y Lilacs, utilizando las palabras claves descritas y aplicando una técnica en bola de nieve, y se seleccionaron los artículos más relevantes.
Resultados. El órgano seleccionado debe asegurar una adecuada red vascular, mantener la función deglutoria y tener los menores riesgos posibles. Cada sustituto tiene ventajas particulares, pero todos generan complicaciones a corto y largo plazo. El estómago es el más frecuentemente usado, sin embargo, el reflujo gastroesofágico y la gastroparesia pueden presentarse en un número importante de pacientes. El colon requiere diversos estudios preoperatorios y cada segmento tiene sus características particulares para el ascenso; a largo plazo puede alargarse, tornarse dilatado y tortuoso, afectando la calidad de vida. El yeyuno supercargado permite un adecuado ascenso sin tensión, pero implica una técnica quirúrgica más compleja.
Conclusiones. El tubo gástrico es la primera opción, por su menor complejidad técnica y buenos desenlaces. De no estar disponible, se cuenta como alternativas con los diferentes segmentos del colon, el yeyuno supercargado o los colgajos musculocutáneos. Las complicaciones asociadas a estos procedimientos no son despreciables, por lo que se debe tener muy en cuenta la experiencia del grupo quirúrgico.
Descargas
Referencias bibliográficas
Jafari MD, Halabi WJ, Smith BR, Nguyen VQ, Phelan MJ, Stamos MJ, et al. A decade analysis of trends and outcomes of partial versus total esophagectomy in the United States. Ann Surg. 2013;258:450-8. https://doi.org/10.1097/SLA.0b013e3182a1b11d
Maish MS, DeMeester SR. Indications and technique of colon and jejunal interpositions for esophageal disease. Surg Clin North Am. 2005;85:505-14. https://doi.org/10.1016/j.suc.2005.01.014
Spitz L, Coran AG. Esophageal replacement. En: Coran AG, Caldamone A, Adzick NS, Krummel TM, Laberge JM, Shamberge R, editors. Pediatric Surgery. Seventh edition. Philadelphia: Mosby; 2012. Chapter 71. p. 927-38. https://doi.org/10.1016/B978-0-323-07255-7.00071-4
Yan D, Zheng H, Wang P, Yin Y, Zhang Q, Zhang L, et al. Surgical outcomes of two different reconstruction routes for esophagectomy in esophageal cancer patients: A meta-analysis. Dis Esophagus. 2022;35:doab070. https://doi.org/10.1093/dote/doab070
Booka E, Takeuchi H, Morita Y, Hiramatsu Y, Kikuchi H. What is the best reconstruction procedure after esophagectomy? A meta-analysis comparing posterior mediastinal and retrosternal approaches. Ann Gastroenterol Surg. 2023;7:553-64. https://doi.org/10.1002/ags3.12685
Gust L, De Lesquen H, Bouabdallah I, Brioude G, Thomas PA, D’journo XB. Peculiarities of intra-thoracic colon interposition-eso-coloplasty: Indications, surgical management and outcomes. Ann Transl Med. 2018;6:41. https://doi.org/10.21037/atm.2017.06.10
Haverkamp L, Seesing MFJ, Ruurda JP, Boone J, Hillegersberg RV. Worldwide trends in surgical techniques in the treatment of esophageal and gastroesophageal junction cancer. Dis Esophagus. 2017;30:1-7. https://doi.org/10.1111/dote.12480
Seineldin S, Seineldin CA. Reemplazo total del esófago. 1a ed. Buenos Aires: ediciones Corpus; 2012.
Hung PC, Chen HY, Tu YK, Kao YS. A comparison of different types of esophageal reconstructions: A systematic review and network meta-analysis. J Clin Med. 2022;11:5025. https://doi.org/10.3390/jcm11175025
Irino T, Tsekrekos A, Coppola A, Scandavini CM, Shetye A, Lundell L, et al. Long-term functional outcomes after replacement of the esophagus with gastric, colonic, or jejunal conduits: A systematic literature review. Dis Esophagus. 2017;30:1-11. https://doi.org/10.1093/dote/dox083
Akiyama H, Miyazono H, Tsurumaru M, Hashimoto C, Kawamura T. Use of the stomach as an esophageal substitute. Ann Surg. 1978;188:606-10. https://doi.org/10.1097/00000658-197811000-00004
Sun S, Wang Z, Huang C, Li K, Liu X, Fan W, et al. Different gastric tubes in esophageal reconstruction during esophagectomy. Esophagus. 2023;20:595-604. https://doi.org/10.1007/s10388-023-01021-z
Shirakawa Y, Noma K, Maeda N, Ninomiya T, Tanabe S, Kikuchi S, et al. Clinical characteristics and management of gastric tube cancer after esophagectomy. Esophagus. 2018;15:180-9. https://doi.org/10.1007/s10388-018-0611-2
Dixit J, Subash A, Gowda N, Deepak H, Amanulla. Hand rule of 5 for a robust gastric conduit in minimal access onco-surgery. Indian J Surg Oncol. 2021;12:432-6. https://doi.org/10.1007/s13193-021-01323-7
Liebermann-Meffert DMI, Meier R, Siewert JR. Vascular anatomy of the gastric tube used for esophageal reconstruction. Ann Thorac Surg. 1992;54:1110-5. https://doi.org/10.1016/0003-4975(92)90077-h
Zhang M, Zhang C, Wu QC. Health-related quality of life and survival among 10-year survivors of esophageal cancer surgery: Gastric tube reconstruction versus whole stomach reconstruction. J Thorac Dis. 2019;11:3284-91. https://doi.org/10.21037/jtd.2019.08.56
Zhang M, Li Q, Tie HT, Jiang YJ, Wu QC. Methods of reconstruction after esophagectomy on long-term health-related quality of life: A prospective, randomized study of 5-year follow-up. Med Oncol. 2015;32:122. https://doi.org/10.1007/s12032-015-0568-0
Hajibandeh S, Hajibandeh S, McKenna M, Jones W, Healy P, Witherspoon J, et al. Effect of intraoperative botulinum toxin injection on delayed gastric emptying and need for endoscopic pyloric intervention following esophagectomy: A systematic review, meta-analysis, and meta-regression analysis. Dis Esophagus. 2023;36:doad053. https://doi.org/10.1093/dote/doad053
Loo JH, Ng ADR, Chan KS, Oo AM. Outcomes of intraoperative pyloric drainage on delayed gastric emptying following esophagectomy: A systematic review and meta-analysis. J Gastrointest Surg. 2023;27:823-35. https://doi.org/10.1007/s11605-022-05573-w
Nienhüser H, Heger P, Crnovrsanin N, Schaible A, Sisic L, Fuchs HF, et al. Mechanical stretching and chemical pyloroplasty to prevent delayed gastric emptying after esophageal cancer resection —a meta-analysis and review of the literature. Dis Esophagus. 2022;35;doac007. https://doi.org/10.1093/dote/doac007
Clark J, Moraldi A, Moossa AR, Hall AW, DeMeester TR, Skinner DB. Functional evaluation of the interposed colon as an esophageal substitute. Ann Surg. 1976;183:93-100. https://doi.org/10.1097/00000658-197602000-00001
DeMeester TR, Johansson KE, Franze I, Eypasch E, Lu CT, McGill JE, et al. Indications, surgical technique, and long-term functional results of colon interposition or bypass. Ann Surg. 1988;208:460-74. https://doi.org/10.1097/00000658-198810000-00008
Peters JH, Kauer WK, Crookes PF, Ireland AP, Bremner CG, DeMeester TR. Esophageal resection with colon interposition for end-stage achalasia. Arch Surg. 1995;130:632-7. https://doi.org/10.1001/archsurg. 1995.01430060070013
Sato M. Surgery: Esophageal Reconstruction. En: Ando N, ed. Esophageal Squamous Cell Carcinoma: Diagnosis and Treatment.: Singapore: Springer; 2020. p. 197-211. https://doi.org/10.1007/978-981-15-4190-2_12
Reslinger V, Tranchart H, D’Annunzio E, Poghosyan T, Quero L, Munoz-Bongrand N, et al. Esophageal reconstruction by colon interposition after esophagectomy for cancer analysis of current indications, operative outcomes, and long-term survival. J Surg Oncol. 2016;113:159-64. https://doi.org/10.1002/jso.24118
Braghetto I, Cardemil G, Csendes A, Domínguez C, Musleh M, Korn O, et al. Reconstitución de tránsito esofágico con interposición de colon derecho. Rev Chil Cir. 2015;67:271-7. http://dx.doi.org/10.4067/S0718-40262015000300006
Brown J, Lewis WG, Foliaki A, Clark GWB, Blackshaw GRJC, Chan DSY. Colonic interposition after adult oesophagectomy: systematic review and meta-analysis of conduit choice and outcome. J Gastrointest Surg. 2018;22:1104-11. https://doi.org/10.1007/s11605-018-3735-8
Thomas PA, Gilardoni A, Trousse D, D’Journo XB, Avaro JP, Doddoli C, et al. Colon interposition for oesophageal replacement. Multimed Man Cardiothorac Surg. 2009:603:mmcts.2007.002956. https://doi.org/10.1510/mmcts.2007.002956
Rice TW. Right colon interposition for esophageal replacement. Operative Tech Thorac Cardiovasc Surg. 1999;4:210-21. https://doi.org/10.1016/S1522-2942(07)70118-6
Kuwabara S, Kobayashi K, Uehara H, Aoki M, Kubota A, Komatsu M, et al. Ileo-right colonic reconstruction preserving all four colonic vessels after esophagectomy for cancer. Updates Surg. 2021;73:2239-46. https://doi.org/10.1007/s13304-021-01033-3
Fürst H, Hartl WH, Löhe F, Schildberg FW. Colon interposition for esophageal replacement: An alternative technique based on the use of the right colon. Ann Surg. 2000;231:173-8. https://doi.org/10.1097/00000658-200002000-00004
Boukerrouche A. Left colonic graft in esophageal reconstruction for caustic stricture: Mortality and morbidity. Dis Esophagus. 2013;26:788-93. https://doi.org/10.1111/j.1442-2050.2012.01383.x
Braghetto I, Figueroa-Giralt M, Sanhueza B, Lanzarini E, Sepúlveda S, Erazo C, et al. Faringo-íleo-colo anastomosis con suplemento vascular microquirúrgico en reconstrucción del tracto digestivo superior. Rev Chil Cir. 2018;70:266-72. http://dx.doi.org/10.4067/s0718-40262018000300266
Cheng B, Chen K, Gao S, Tu Z. Colon interposition. En: Lange J, Siewert JR, eds. Esophageal carcinoma. State of the Art. Recent Results in Cancer Research. Berlin: Springer. 2000;155:151-60. https://doi.org/10.1007/978-3-642-59600-1_16
Noguchi T, Uchida Y, Hashimoto T, Wada S, Suko T, Suzuki M. [Reconstruction of the cervical esophagus by interposition of the transverse colon]. Nihon Geka Gakkai Zasshi. 2001;102:647-52.
Dantas RO, Mamede RCM. Motility of the transverse colon used for esophageal replacement. J Clin Gastroenterol. 2002;34:225-8. https://doi.org/10.1097/00004836-200203000-00005
Wormuth JK, Heitmiller RF. Esophageal conduit necrosis. Thorac Surg Clin. 2006;16:11-22. https://doi.org/10.1016/j.thorsurg.2006.01.003
Esmonde N, Rodan W, Haisley KR, Joslyn N, Carboy J, Hunter JG, et al. Treatment protocol for secondary esophageal reconstruction using ‘supercharged’ colon interposition flaps. Dis Esophagus. 2020;33:doaa008. https://doi.org/10.1093/dote/doaa008
Braghetto I, Csendes A, Amat J, Parada M, Schutte H, Lizana C, et al. Reconstrucción del tránsito esofágico con interposición de colon. Rev Chil Cir. 1994;46:477-84.
AbouZeid AA, Zaki AM, Safoury HS. Posterior cologastric anastomosis: An effective antireflux mechanism in colonic replacement of the esophagus. Ann Thorac Surg. 2016;101:266-73. https://doi.org/10.1016/j.athoracsur.2015.06.074
Strauss DC, Forshaw MJ, Tandon RC, Mason RC. Surgical management of colonic redundancy following esophageal replacement. Dis Esophagus. 2008;21:E1-E5. https://doi.org/10.1111/j.1442-2050.2007.00708.x
Horváth ÖP, Cseke L, Papp A, Pavlovics G, Vereczkei A. [Complications of esophageal replacement]. Orvosi Hetilap. 2023;164:243-52. https://doi.org/10.1556/650.2023.32715
Baldwin D, Gonzalez SR, Anand S. Esophageal reconstruction. En: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024. Disponible en: https://www.ncbi.nlm.nih.gov/books/NBK564336/
Cano FA, Jaime M, Wolff G. Autotrasplante de yeyuno en estenosis del esófago cervical. Informe de 1 caso. Rev Colomb Cir. 1991;6:105-8.
Besharat S, Jabbari A, Semnani S, Keshtkar A, Marjani J. Inoperable esophageal cancer and outcome of palliative care. World J Gastroenterol. 2008;14:3725-8. https://doi.org/10.3748/wjg.14.3725
Swisher SG, Hofstetter WL, Miller MJ. The supercharged microvascular jejunal interposition. Semin Thorac Cardiovasc Surg. 2007;19:56-65. https://doi.org/10.1053/j.semtcvs.2006.11.003
Ascioti AJ, Hofstetter WL, Miller MJ, Rice DC, Swisher SG, Vaporciyan AA, et al. Long-segment, supercharged, pedicled jejunal flap for total esophageal reconstruction. J Thorac Cardiovasc Surg. 2005;130:1391-8. https://doi.org/10.1016/j.jtcvs.2005.06.032
Stephens EH, Gaur P, Hotze KO, Correa AM, Kim MP, Blackmon SH. Super-charged pedicled jejunal interposition performance compares favorably with a gastric conduit after esophagectomy. Ann Thorac Surg. 2015;100:407-13. https://doi.org/10.1016/j.athoracsur.2015.03.040
Blackmon SH, Correa AM, Skoracki R, Chevray PM, Kim MP, Mehran RJ, et al. Supercharged pedicled jejunal interposition for esophageal replacement: A 10-year experience. Ann Thorac Surg. 2012;94:1104-13. https://doi.org/10.1016/j.athoracsur.2012.05.123
Mohan AT, Mahajan NN, Mardini S, Blackmon SH. Outcomes of standardized protocols in supercharged pedicled jejunal esophageal reconstruction. Ann Thorac Surg. 2023;115:210-9. https://doi.org/10.1016/j.athoracsur.2022.05.048
Sharma S, Gupta DK. Surgical techniques for esophageal replacement in children. Pediatr Surg Int. 2017;33:527- 50. https://doi.org/10.1007/s00383-016-4048-1
Platt E, McNally J, Cusick E. Pedicled jejunal interposition for long gap esophageal atresia. J Pediatr Surg. 2019;54:1557-62. https://doi.org/10.1016/j.jpedsurg.2018.10.108
Doki Y, Okada K, Miyata H, Yamasaki M, Fujiwara Y, Takiguchi S, et al. Long-term and short-term evaluation of esophageal reconstruction using the colon or the jejunum in esophageal cancer patients after gastrectomy. Dis Esophagus. 2008;21:132-8. https://doi.org/10.1111/j.1442-2050.2007.00738.x
Gaur P, Blackmon SH. Jejunal graft conduits after esophagectomy. J Thorac Dis. 2014;6(Suppl 3):S333-S340. https://doi.org/10.3978/j.issn.2072-1439.2014.05.07
Merritt RE. Conduit selection for reconstruction after esophagectomy for esophageal cancer. Surg Oncol Clin N Am. 2024;33:549-56. https://doi.org/10.1016/j.soc.2024.01.001
Miyawaki Y, Tachimori H, Nakajima Y, Sato H, Fujiwara N, Kawada K, et al. Surgical outcomes of reconstruction using the gastric tube and free jejunum for cervical esophageal cancer: Analysis using the National Clinical Database of Japan. Esophagus. 2023;20:427-34. https://doi.org/10.1007/s10388-023-00997-y
Mays AC, Yu P, Hofstetter W, Liu J, Xue A, Klebuc M, et al. The supercharged pedicled jejunal flap for total esophageal reconstruction: A retrospective review of 100 cases. Plast Reconstr Surg. 2019;144:1171-80. https://doi.org/10.1097/PRS.0000000000006171
Grant WB. Cancer incidence rates in the US in 2016- 2020 with respect to solar UVB doses, diabetes and obesity prevalence, lung cancer incidence rates, and alcohol consumption: An ecological study. Nutrients. 2024;16:1450. https://doi.org/10.3390/nu16101450
Mohan AT, Mardini S, Blackmon SH. Supercharged jejunal interposition. Thorac Surg Clin. 2022;32:529-40. https://doi.org/10.1016/j.thorsurg.2022.07.007
Watt FM, Huck WTS. Role of the extracellular matrix in regulating stem cell fate. Nat Rev Mol Cell Biol. 2013;14:467-73. https://doi.org/10.1038/nrm3620
Arakelian L, Kanai N, Dua K, Durand M, Cattan P, Ohki T. Esophageal tissue engineering: From bench to bedside. Ann N Y Acad Sci. 2018;1434:156-63. https://doi.org/10.1111/nyas.13951
Gaujoux S, Le Balleur Y, Bruneval P, Larghero J, Lecourt S, Domet T, et al. Esophageal replacement by allogenic aorta in a porcine model. Surgery. 2010;148:39-47. https://doi.org/10.1016/j.surg.2009.12.002
Dua KS, Hogan WJ, Aadam AA, Gasparri M. In-vivo oesophageal regeneration in a human being by use of a non-biological scaffold and extracellular matrix. Lancet. 2016;388:55-61. https://doi.org/10.1016/S0140-6736(15)01036-3
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2024 Revista Colombiana de Cirugía

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
Todos los textos incluidos en la Revista Colombiana de Cirugía están protegidos por derechos de autor. Las opiniones expresadas en los artículos firmados son las de los autores y no coinciden necesariamente con las de los directores o los editores de la Revista Colombiana de Cirugía. Las sugerencias diagnósticas o terapéuticas como elección de productos, dosificación y métodos de empleo corresponden a la experiencia y al criterio de los autores.
| Estadísticas de artículo | |
|---|---|
| Vistas de resúmenes | |
| Vistas de PDF | |
| Descargas de PDF | |
| Vistas de HTML | |
| Otras vistas | |











.jpg)
